US regulations for dual-use research
The Obama administration on Wednesday issued new guidelines intended to strengthen the oversight of federally funded biology research that could inadvertently produce bioweapons (New York Times). Read more »
Concerns over consent guidance
The US FDA was flooded with comments on its draft guidance seeking to amend the informed consent process – some saying guidance will further confuse patients while others took issue with ommissions (Outsourcing Pharma). Read more »
Update: More discussion of detail
Greater demands on clinical research
The quality of research will have a greater effect on how much funding the state will provide. This is the result of the new ALF deal between the state and the county councils (The Government). Read more »
State centre for RCT's
A state centre for clinical trials and other clinical research will be created in Göteborg. It will have 50 millions a year to strenghten cooperation between health care, industry and academy (The Government). Read more »
Human DNA belongs to no one
Following contrasting rulings on the patentability of genes issued in US and Australia, Luigi Palombi explores the historical background to this area of jurisprudence (The Guardian) Read more »
Bioethics Film Festival Edinburgh
Are human embryos just piles of cells or persons like us? But what is a person anyway? These are some of the questions which film-goers will be invited to explore and debate at the 10th International Biomedical Ethics Film Festival in November in Edinburgh (BioEdge). Read more »
Use of unregistered interventions for Ebola
Summary of the WHO panel discussion on ethical considerations for use of unregistered interventions for Ebola virus disease. Read more »
Japanese stemcell scientist dead
A leading Japanese stem cell researcher has committed suicide in the wake of retractions of papers which he co-authored (BioEdge). Read more »
Give your views on clinical GMO test!
According to the Swedish law, the public must be informed about pending decisions to use GMO drugs in clinical trials. The Swedish Medical Products Agency now gives you the opportunity to have your say (Medical Products Agency). Read more »
In a recent post on his Practical Ethics blog, Oxford bioethicist Julian Savulescu has defended controversial ideas on geoengineering on the grounds that it could be the only way to combat climate change (Practical Ethics). Read more »
FDA debates trial-data secrecy
US drug regulator weighs up merits of disclosing preliminary results (Nature News). Read more »
Human Eggs Should Be Patentable
Unfertilised human eggs that can't develop into human beings are generally not "human embryos" within the meaning of the EU directive on the legal protection of biotechnological inventions, a 17 July European Court of Justice Advocate General opinion said (IP Watch). Read more »
Alarm over biosafety blunders
The head of the U.S. Centers for Disease Control and Prevention has held an alarming press conference, describing lab mistakes with three deadly pathogens and vowing to "do everything in my power to make sure that nothing like this happens again" (Science). Read more »
Research teams clash over too-similar MERS papers
Scientists working on the deadly MERS virus are puzzled by 2 papers in separate journals that tell the same story and are based on data from the very same patient (ScienceInsider). Read more »
Church let 2,000 children be used in experiments
More than 2000 Irish children in religious run homes were subjected to drugs trials in the 1930s according to a shocking new report (IrishCentral). Read more »
New technology could replace animal testing
Researchers from Harvard University's Wyss Institute are developing 'bio-chips' that replicate the functioning of organs in the human body (BioEdge). Read more »
No stop to funding embryonic stem cell research
The European Commission has rejected a petition calling for a halt to the funding of research involving the 'presupposed destruction' of human embryos (BioNews). Read more »
Common protection of patents
The Swedish Riksdag has said yes to a 2015 start for EU patents in Sweden and the creation of a European patent court with a bransch in Stockholm (Riksdagen). Read more »
US human subjects research oversight "invisible"
The Office for Human Research Protections (OHRP) opened just one investigation into allegations of violations of human subject protections in all of 2013 (Report on Research Compliance).
Read more »
Another consent debacle revealed
The latest revelation comes from Vienna, Austria, where researchers in the 50's deliberately infected hospitalised children with malaria in the hope of finding a cure for syphilis (BioEdge). Read more »
RIKEN to check 20 000 papers
Shockwaves emanating from allegations of image manipulation and plagiarism in two Nature papers continue to ripple through RIKEN, the Japanese institute at the center of the ongoing controversy. RIKEN president Ryoji Noyori has asked all group leaders to check their previous publications. The directive covers at least 20,000 publications (ScienceInsider). Read more »
Success cloning with embryo cells
Scientists have taken skin cells from a woman suffering from type 1 diabetes, reprogrammed them into embryonic stem cells, and then converted those cells into insulin-producing cells in mice, according to a new study (Los Angeles Times). Read more »
Campaign for Air France
After animal groups has targeted the only airline shipping pimates to be used for research, the Foundation for Biomedical Research has started a campaign in support of the company. Read more »
Plus: LA Weekly has written an article on this issue
STAP Cell Research Paper Investigation
Allegations and concerns over two cell research articles in Nature by researchers at the RIKEN Center for Developmental Biology (CDB), have been investigated by a committee that claims misconduct took place (RIKEN). Read more »
Ill-informed arguments on animal research
Claiming that animals are poor predictors of human responses to drugs fundamentally misunderstands how animals are used; to test the safety of the drug, not its efficacy (The Parliament Newspaper).
Read more »
Trust dependent on more than guidelines
Research ethics risks developing into institutionalized distrust - something that threatens researchers' moral competence and integrity, scholars at the Centre for Research Ethics and Bioethics say (Uppsala University). Read more »
EP Vote On Compulsory CT Data Publishing
The European Parliament is scheduled to vote on 3 April on amended draft legislation that would oblige pharmaceutical companies to publish all clinical trial data in a publicly accessible database (Intellectual Property Watch). Read more »
E.U. Privacy Bill Would Hamper Research
Biomedical researchers in Europe are worried about provisions to make it more difficult to use patients' data without their consent. That would render some important studies impractical or impossible, scientists say (Science). Read more »
US scientists covered up war crimes
How US scientists led a campaign to grant immunity from prosecution for Japanese doctors guilty of horrendous crimes (BioEdge). Read more »
More open access journals
After Nature having created one, now the publisher of Science is to launch its first open-access journal in early 2015 (Nature newsblog). Read more »
Acid-bath stem-cell study under investigation
Japanese research institute launches inquiry after allegations of irregularities in blockbuster papers (Nature News). Read more »
Elsevier opens its papers to text-mining
Researchers welcome easier access for harvesting content, but some spurn tight controls (Nature News). Read more »
A step closer to clinical trial reform
European parliament reaches provisional agreement on new rules for clinical trial authorization procedures (Nature). Read more »
The Swedish academy is not free
This is said by representatives of Swedish research in an opinion piece published in Uppsala Nya Tidning. Read more »
Divulging DNA Secrets of Dead Stirs Debate
As gene sequencing advances, more and more research studies turn up gene mutations that can impact health. If the volunteer dies, what to do with DNA findings that may impact their survivors? (Science News). Read more »
Key details omitted in animal research
Preclinical animal studies often lack important details needed for assessing and replicating the work, and they use statistical calculations that are not fit for purpose, a new analysis of recent papers shows (Nature News). Read more »
ECT crisis delays research
The regional ethics review board in Uppsala has cancelled meetings in january. Now several research projects risk long delays (UNT). Read more »
New organisation for clinical studies
To strenghten Sweden's position in clinical research, a national system of co-ordination today was suggested by a public inquiry (Ministry of Education). Read more »
Scrap "luxury journal" system, says Nobel Prize winner
Randy Schekman, a US biologist who recently received his prize in Stockholm, said his lab would no longer send research papers to Nature, Cell and Science (BioEdge). Read more »
Revision of Declaration of Helsinki published
An updated version of the Helsinki Declaration is here - but it is also met with fierce criticism (BioEdge). Read more »
China's Publication Bazaar
Going undercover, Science reveals a massive fraudulent trade in scientific papers and authorships in China. Read more »
SND's handling of personal data not allowed
A court now affirms the Swedish Data Inspection Board's decision that the handling of personal data by Svensk Nationell Datatjänst is unlawful (registerforskning.se). Read more »
Mandatory videorecording of consent
The India Health Ministry has made audio-visual recording of the informed consent of each subject mandatory in a clinical trial. This is in addition to obtaining his/her written consent (The Hindu).
Read more »
Government for better animal protection
The Swedish Government has put forth a proposition for more animal protection, suggesting better protection of animals in research from 1 of April 2014 (Swedish Government). Read more »
Drug trial secrecy should end
Europe's medicines regulator has come out fighting for greater transparency for clinical trials, arguing that its controversial policy to end data secrecy will be a boon to drug developers (EurActiv). Read more »
Another unethical study exposed
Here's a familiar script: medical researchers in the 1950s in a democratic country conduct forgotten experiments which yield no useful data on a vulnerable population (BioEdge). Read more »
Where marmosets get Parkinson's
As a UK debate is launched on animal research, Robin McKie meets the London scientists whose work goes to the heart of an ethical controversy (The Guardian). Read more »
Knowledge needed about nanomaterials
Nanomaterials is important but it's effects on man and environment need to be researched and the law must change (Ministry of Environment)). Read more »
Animal research: a balancing act
Gains in human health come at the expense of animals in the lab. But denying those gains by hampering animal research could be far costlier (Nature Medicine editorial). Read more »
Shutdown Halts Research Projects
Just hours into the government shutdown, US federal agencies shut their doors - resulting in something akin to short-term paralysis (Huffington Post). Read more »
Mystery over obesity 'fraud'
Researcher baffled after his results appear in bogus paper (Nature News). Read more »
Open access reaching ‘tipping point’
The global shift towards making research findings available free of charge for readers, so-called ‘open access’, was confirmed recently in a EU study (The Portugal News Online). Read more »
Ethics in HIV cure research
Johns Hopkins expert Jeremy Sugarman says crucial ethics concerning risk and confidentiality should be considered in HIV cure research (News Medical). Read more »
EU pushes through Unified Patent Court
Brussels has paved the way for a specialised European patent court to solve disputes in one instance and avoid multiple litigation cases in up to 28 different national courts (EurActiv). Read more »
US brain project puts focus on ethics
Unsettling research advances bring neuroethics to the fore (Nature News). Read more »
Swedish bid to strenghten clinical trials
A Swedish campaign to strenghten clinical research is presented (Swedish Government). Read more »
Critics skeptical to H7N9 studies
22 flu scientists make a case for launching potentially risky gain-of-function experiments involving the H7N9 avian influenza virus, but critics say risks outweigh potential benefits (Science). Read more »
Update 2013-08-19: Extra Oversight for H7N9 Experiments
Balancing privacy with public benefit
Maximizing access to research data will greatly benefit science, and users can help to establish universal principles on how to do it (Nature column). Read more »
Trials Paused as India Adopts New Rules
India suspends new clinical trials as it tightens ethics and safety rules (Nature). Read more »
Research scandals then and now
Bioedge reveals research performed both decades ago and very recently that are not up to scrutiny: research on Canadian indians in the 40's and 50's and resent research in China by GlaxoSmithKlein.
New tools match patients - clinical trials
The majority of Americans are positive to take part in a clinical trial but nevertheless there's a shortage of enrollment. New tools that automatically prescreen patients for trials based on their electronic medical records and email matches to doctors could help solve the problem (Nature Medicine). Read more »
Threats to researchers will be handled
So far there have been little coordination, but now Rikskrim and SÄPO will make efforts to address the problem with extremistic animal rights activists (LifeScience Sweden). Read more »
New risks of discrimination: a call of the IBC
In this movie filmed in September 2012, several renowned experts, all members of the International Bioethics Committee highlight the new risks of discrimination and the new responsibilities induced by the advances in biomedicine (Youtube). Read more »
Supreme Court says human genes cannot be patented
The Supreme Court has ruled that companies cannot patent parts of naturally-occurring human genes, a decision with the potential to profoundly affect the emerging and lucrative medical and biotechnology industries (CBS News). Read more »
Publish trial results researchers don’t
If gaps and errors in research reporting are not put right by the original authors within a year, independent researchers should take on the task, a team of medical scientists has said in the BMJ.
Read more »
Mikrochip gives alternative to animal testing
Researchers from Lund have developed a new method for chemical testing that uses human cells cultived in the lab (Forskning.se).
Read more »
Global alliance to boost gene data-sharing
Leading international healthcare, research, funding, and technology organisations will work together in a non-profit alliance to enable large-scale sharing of genetic data (BioNews). Read more »
Study identifies how to get consent informed
A trial at the University of Michigan showed that measures to increase readability led to a 75% better understanding risks and benefits of the trial (Bioedge). Read more »
Clinical trials: clearer rules, better protection
Draft EU rules on clinical trials were endorsed by the Public Health Committee last week. A regulation designed to encourage research whilst protecting patients' rights is to replace an existing directive with simpler, more uniform rules, making specific provision for low-risk trials and clarifying duties of ethics committees (Europarl). Read more »
Dealing with research misconduct
Reconsider the present system for reporting and investigating research misconduct, say the Research Council and SUHF in a common petitition to the Swedish Government (Vetenskapsrådet). Read more »
Threats common for animal experimentists
Burned cars, home visits and angry calls are everyday experiences for researchers experimenting with animals, but the police has no action plan for putting an end to this. Academia and industry are now fed up and want stronger efforts (LifeScience Sweden).
Read more »
Pushes for more transparency
The EU Commission's proposed revision on the Clinical Trials Directive is important, but does not go far enough, says the Cochrane Collaboration, which advocates more transparency in clinical trials (EurActiv). Read more »
EU stops sharing of Humira-data
EMA, working for greater transparency, has been ordered to not release raw data from clinical studies by the EU court (Life Science Sweden). Read more »
No longer need for review
From the 1st of March there is no longer any obligatory reporting of certain research projects to the Data Inspection Board for pre-review (Etikprövningsnämnderna). Read more »
Prison sentence for research misconduct
A man in the UK is sentenced to three months in prison for manipulating preclinical data that was used for clinical trials (Life Science Sweden). Read more »
Calls for ethics to ease suspicion of industry
The suspicion that industrial involvement in science is only geared towards profit threatens to derail European policymaking and new ethical standards could help solve the issue, the EU’s chief scientific advisor has said (EurActiv). Read more »
The Ethics of Resurrecting Extinct Species
At some point, scientists may be able to bring back extinct animals, and perhaps early humans, raising questions of ethics and environmental disruption (ScienceDaily). Read more »
Clinical trials directive: The Parliament's political dilemma
The most contentious political questions in the Clinical Trials Directive relate to disclosure – whether, how and when the results of clinical trials should be made public and whether pharmaceutical companies can claim ownership over the data generated by them, writes Jim Murray (EurActiv). Read more »
Stronger protection for whistleblowers
A public inquiry will investigate how to strenghten the protection of people who blow the whistle on misdeeds in the workplace and suggest better regulations (Swedish Government). Read more »
Industry better at handling conflicts
In the US there already exist registers over experts and doctors getting paid by drug companies. Now the European drug makers will do the same. (Life Science Sweden). Read more »
Guiding responsible geoengineering
Harvard, UCLA experts propose new structure for regulation of geoengineering research (EurekAlert!). Read more »
He puts misconduct on the map
Interview with CODEX' editor about his new book on publication ethics (Dagens Medicin). Read more »
Roche not supportive of alltrials campaign
Campaigners for full transparency of all clinical trial data have responded with incredulity to a statement from the drug company Roche saying that it would continue to hold back certain information and results (BMJ). Read more »
Open access new US federal policy
After deliberating for more than 3 years on ways to expand public access to taxpayer-funded research papers, the White House is finally taking action. Agencies are asked to make papers on research that they fund freely available online within 12 months after the results appear in a journal (Science). Read more »
New EU regulation threat to research
At least according to the 16 professors and representatives for Disc and Svensk epidemiologisk förening that discuss the proposed EU regulation on personal data, and argues that it will result in changes that make much medical research impossible (SvD Brännpunkt). Read more »
US announces dual use policies
The U.S. government have released two new documents to guide researchers in carrying out dual use research of concern (EurekAlert!). Read more »
Proposed research regulation rejected by DI
The Swedish Data Inspection Board has reviewed the proposal for a new law regulating popoulation-based research. It has many deficits, they claim, which is why it cannot be endorsed.
Read more »
Trauma patients support concent exception
Traumatic injury is the leading cause of death for people under 40, but few medical interventions for these injuries have been studied, because patients are typically unable to consent to participate. A new University of Pennsylvania study indicates that peoples are willing to be enrolled in these studies without express consent. Read more »
Register research and integrity protection
A new public inquiry will ask how the unique Swedish conditions for register based research better can be utilized. Bengt Westerberg has been appointed (Ministry of Education). Read more »
The lifting of the moratorium on research to engineer strains of the H5N1 avian influenza virus must not be seen as closure of the debate on such 'dual-use' research, writes Nature in an editorial. Read more »
A Little Digging Unmasks Donor Names
Experts identify people donating their DNA by matching Y-chromosome markers to genealogy sites; researchers' privacy promises 'empty' (Wall Street Journal). Read more »
Research target for electronic espionage
Industrial espionage targetting Swedish national interests is on the rise, according to FRA. Among highly technologically and research driven areas that are targeted are found drug companies and research institutions (Dagens Medicin). Read more »
All Trials Registered | All Results Reported
A petitition that call on governments, regulators and research bodies to implement measures to always register all trials past and present and report the full methods and results. Homepage
Redefining Healthcare & Research Ethics
A group of interdisciplinary healthcare experts rejects an ethical paradigm that has guided research ethics since the 70s and calls for morally obligatory participation in a “learning healthcare system” (Johns Hopkins). Read more »
Stem Cell Lawsuit Finally Over
The Supreme Court today rejected a request to ban U.S.-funded research on human embryonic stem cells, which brings to an end a legal battle that has cast a shadow over hESC studies for over 3 years (Science Insider). Read more »
Fraudster Blog Author Outed
The author of a popular Web site that claimed to identify manipulated images — and the scientists behind them — has announced that he will suspend posting following threats of legal action (Science Insider). Read more »
New management for CEPN finalized
Now the Swedish Government has decided upon who should be part of the new leadership for Centrala etikprövningsnämnden. Only four persons remain. (Dagens Medicin). Read more »
Critique against Nagoya protocol proposal
The EU proposal on how to implement the Nagoya protocol (see news item dated october 11) is criticised by the Swedish Parliament. Read more »
Expert group to examine biotech patent law
The European Commission will be building a new team with 15 experts, to examine the development and implications of patent law in the field of biotechnology and genetic engineering (EU Commission). Read more »
Members of central animal ethics committee appointed
The committee starts work on January 1, 2013 (The Swedish Government). Read more »
EU has voted for a community patent
The European Parliament endorsed a community patent and a corresponding court, the recent vote revealed. (The Swedish Government). Read more »
Researchers fail to inform subjects
The Swedish Data Inspection Board has inspected research projects and found that there are deficiences regarding how research subjects are informed about data handling and their rights. (Data Inspection Board). Read more »
Plans for H5N1 Reviews Ruffle Researchers
Researchers are giving mixed reviews to a draft U.S. government plan to subject some grant requests for studies involving the H5N1 avian influenza virus to special reviews—and perhaps even require the work to be kept secret (Science). Read proposal
EU Patent & Court Finally Approved?
A new proposal by European Union governments could signal the end of a years-long struggle for a unified European patent and patent court. (Intellectual Property Watch). Read more »
Super computer replaces animal experiments
With the help of advanced computer simulations, KTH researchers will reduce the number of animals tested by having super computers replace former ineffective methods (Forskning.se). Read more »
Should 'open evaluation' be added to 'open access'?
An ebook of 18 articles make the case for a radical change in scientific peer review and publishing (EurekAlert!) Read more »
Samples discarded unnecessarily
The unclear rules of biobanking make companies throw away potentially valuable material. But the Government are in no hurry to change the law (Life Science Sweden). Read more »
Patent legislation to adopt to EU changes
The negotiations on how to improve the European patent system are now finishing and thus the Swedish Government has decided upon a public inquiry which should suggest needed legislative changes as well as a new patent act. (Mitt i juridiken). Read more »
First gene therapy approved
The EU Commission approves Glybera, developed by Dutch company Uniqure, in order to help patienbts with LPLD (Life Sccience Sweden). Read more »
Better regulation and less bureaucracy
That is the goal for Science Europe, an organization that will replace European Science Foundation (Curie). Read more »
Possibly less paper work
The Swedish Government proposes that the present demand for pre-screening of data handling in certain research is dropped (Dagens Medicin). Read more »
Researcher cleared of misconduct
Evidence is too weak, says Centrala etikprövningsnämnden and closes the investigation (Life Sccience Sweden). Read more »
More risktaking research needed2012-10-12
The part of public research funded in competition will be doubled but, more importantly, the way to evaluate proposals will change to a peer-review model (Swedish Government). Read more »
Draft EU regulation on biopiracy & research
The European Commission has introduced a draft Regulation to implement the Nagoya Protocol (Biodiversity Policy & Practice). Read more »
Misconduct main cause of retractions
A survey has found that two-thirds of retracted life-sciences papers were stricken from the scientific record because of misconduct and that journals sometimes soft-pedal the reason (Nature News).
Read more »
New rules on animal testing forces alternative methods
Stricter rules in the EU on animal testing are pressing researchers into finding alternative methods for the evaluation of chemicals. Some have already been evolved and more will come (Life Science Sweden). Read more »
Lab-animal flights squeezed
Two biggest cargo carriers affirm that they will not ship mammals and non-human primates, as activist pressure mounts to stop research-animal airlifts (Nature News). Read more »
Video records of consent mandatory in India
If you run a clinical trial in India, it will be mandatory to do audiovisual recordings of the whole informed consent process, to make sure trials are ethical (Pharmabiz.com). Read more »
Government inquiry on nanomaterials
The Swedish Government has decided to appoint a public inquiry on how to use nanomaterials in a safe way (Ministry of Environment). Read more »
250 dead because of Swedish law
This has been calculated by professors in anaesthesia and intensive care by looking at the delay for important research results resulting from Swedish law not accepting research without informed consent in a study (Dagens Medicin). Read more »
Overstated and unfair critique
The criticism made of the Central Ethical Review Board can't be rejected completely, but it is overstated and unfair, writes Johan Munck and Gisela Dahlquist. (Dagens Medicin). Read more »
Ethical Review Board criticized
Dagens Medicin has revealed questionable practices regarding document handling at the Central Ethical Review Board - and the board might now be further scrutinized. (Dagens Medicin).
Read more »
Ending Honorary Authorship
Honorary authorship must no longer be tolerated. Concerted efforts by institutions, authors, and journals are needed to put an end to this fraudulent and unethical practice (Nature Editorial). Read more »
Data Inspection Board still critical of SND
In a statement to the court, the Swedish Data Inspection Board keep to the decision regarding Swedish National Data Service; it is a violation of the Swedish act on personal data (SND). Read more »
U.S. stem cell research wins in court
A U.S. appeals court upheld the legality of federally funded research on human embryonic stem cells — the latest in a string of wins for NIH in a 3-year legal battle with pro-life groups. (ScienceInsider). Read more »
Gene patent case ruled for Myriad
In the latest instalment of a highly contested case, the US Federal Circuit Court of Appeals in Washington DC upheld Myriad Genetics' right to patent two genes, BRCA1 and BRCA2, which are used in cancer risk testing. (BioNews). Read more »
Scientists must remember that however irrelevant their involvement in industry might seem to them, others will see it differently — only full disclosure will avert the taint of scandal. (Nature). Read more »
Research ban for surgeons after experiment
In an attempt to help people with advanced brain cancer, surgeons deliberately infected them with "probiotic" bacteria to stimulate their immune systems. Rather than miraculous recoveries, however, it led to them being banned from conducting human research (New Scientist). Read more »
The Italian manslaughter trial
At the end of May, 8 months after the trial began, all of the indicted Italien scientists took to the witness stand for the first time, offering a variety of defenses in response to the prosecution's questioning about the earthquake warnings (Nature). Read more »
New free plagiarism checker
Recently a new plagiarism checking tool - plagtracker - was released. Link »
Informed consent: A broken contract
As researchers find more uses for data, informed consent has become a source of confusion. Something has to change (Nature). Read more »
Do not censor science in name of biosecurity
Security officials should not be concerned about the publication of mutant-flu research, says bio-weapons expert Tim Trevan (Nature). Read more »
Justice for injured research subjects
Carl Elliott has published an article calling for justice for research subjects. Nearly every other developed country requires treatment or compensation for people who are injured by their participation in a trial, but not the US (NEJM). Read more »
Critique against proposed new ordinance
In a statement, the Swedish Data Inspection Board critcises a new ordinance, proposed in order to make possible register-based research such as the LifeGene project. Read the statement »
Open science and reproducible research
New reports call for scientists to share data and publishers to embrace open access (BMJ). Read more »
EU agreement on common patent
The European Council have reached an agreement on the last remaining issue in the negotiations on a common EU patent - court location (Swedish Government). Read more »
Protecting trial subjects and data integrity
Susan Ellenberg discusses alternative approaches towards evaluating data as it accumulates in clinical trials, and to protecting the integrity and preventing undue risks to participants, as the trial continues (PLoS Medicine). Read more »
Two reports highlight key aspects of the global trend towards open access to research results: who will pay, and how much, to supply what to whom? (Nature) Read more »
Borders of misconduct
A dispute regarding a whitewash of alleged ghostwriting indicates how one can sometimes hide behind the traditional notion of misconduct. (Nature). Read more »
To regulate climate engineering
Scientists are developing geoengineering technologies. But whether these methods eventually succeed in countering climate change, and whether they will be embraced by the wider population, concerns more than scientists alone (Nature). Read more »
New animal protection legislation
The animal welfare legislation will be changed from 2013 to conform with a EU directive, which means for example that the definition of animal experimentation will also include the keeping a genetically changed breed, a classification of animal experiments based on their severity, and the creation of a new central animal ethics committee. Read more »
Reply to all!
Scientists discussing their work through written media, including e-mail, should be aware that they could at any time be asked to reveal their conversations (Nature). Read more »
Discontent with consent
A new type of patient consent promises to galvanize how personal genomic and medical data are shared in open research environments (Nature biotechnology). Read more »
Are researchers truly independent?
Swedish research on the radiation of mobile phones is funded by the industry. Vinnova is trying to act as a barrier to undue influence - but Ny Teknik now points to deficiencies in an article. Read more »
Scientists: your number is up
ORCID scheme will give researchers unique identifiers to improve tracking of publications. (Nature). Read more »
NHS to publish anonymised patient data
Now an information strategy plans to release anonymised patient data to researchers, industry and the public, is underway in the UK (Techweek Europe). Read more »
EU ordinance on data protection discussed
The Nordic data inspection authorities met in Oslo to discuss the suggested data protection regulation - the greatest change to data protection ever envisaged here (Swedish Data Inspection Board). Read more »
Global council aims to coordinate science
Research-agency heads from around the world agree to formulate shared principles to aid collaborations. (Nature). Read more »
California considers DNA privacy law
Lawmakers are weighing a bill aimed at protecting citizens from surreptitious genetic testing but scientists are voicing their concerns that such a law would have a costly and damaging effect on research (Nature). Read more »
Plagiarism charge for Romanian minister
Scandal adds to fears that country’s research reform is in peril (Nature). Read more »
Post-marketing trials challenged
Current research ethics focuses on protecting study participants, but according to bioethicists from Carnegie Mellon University and McGill University, these efforts fail to prevent problems that undermine the social value of research (EurekAlert!). Read more »
Should scientists be more forthcoming about their flaws? Two new books suggest that instead of trying to hide their uncertainties, scientists should show their foibles and flaws for all to see (Slate). Read more »
Bacteria researcher dead by contamination?
Health agencies are investigating the death of a research associate at the Veterans Affairs Medical Center in San Francisco. He died of meningococcal disease, possibly contracted from exposure to bacteria in the lab where he worked (ScienceInsider). Read more »
Publishing risky research
Imperfect global biosafety standards and a threat to researchers' motivations from biosecurity concerns are among the significant risks in current flu research, says Nature after publishing the controversial avian flu research. Read more »
Sweden soft on research misconduct
Still Sweden stand out among the Nordic countries as worst when it comes to investigating alleged research misconduct. The chance for someone outside of the research process to get an investigation is very slim, says former pediatrician Leif Elinder (GP).
Read more »
No again to unspecified research
The Swedish Data Inspection Board have reviwed the Swedish National Data Service and say that the collection of data from research for future unspecified research is against the law on personal data and therefore must stop. Read more »
Risk level decided by research field?
The question arises when observing the american discussion on which fields should have less regulatory burden based on them being low-risk research - now that new rules are proposed for the first time in 20 years (EurekAlert!) Read more »
Concordat for research integrity in the UK
The universities of UK has been working with research councils a.o. to draft a concordat which outlines five important commitments that those engaged in research can make to help ensure that the highest standards of rigour and integrity are maintained.
Read more » (link to draft)
Pressure is growing for open access
The European Commission will propose a plan for open access soon, while the Wellcome Trust and Research Councils UK are cracking down on researchers who don’t comply with their policies (Intellectual Property Watch) Read more »
Journals issue ultimatum in Fujii case
A group of editors representing nearly two dozen medical journals has issued an ultimatum to 7 Japanese institutions that employed disgraced anesthesiologist Fujii: Validate 193 papers or they will be retracted! (Retraction Watch) Read more »
Screening for dual use
The United States now has a formal policy for overseeing taxpayer-funded biomedical research that could be used for good or evil, through new rules that require federal agencies to systematically screen funding proposals for "dual use research of concern" (Nature). Read more »
Panel says flu research is safe to publish
After experiments that made a dangerous flu virus more contagious, a panel of scientific advisers recommends that full details of the research be published (New York Times).
Read more »
EU Clinical Trials Register available at WHO
Information contained in the European Union Clinical Trials Register managed by the European Medicines Agency is now available through the WHO International Clinical Trial Registry Platform. Read more »
Consensus on returning results
A consensus article outlines explicitly "significant new responsibilities" for biobanks concerning the return of incidental findings and individual research results to people whose biospecimens were used in genetic and genomic studies (EurekAlert!) Read more »
Stronger animal protection
The Swedish government proposes a new central ethical committee for the use of animals in research, in order to improve the protection of these animals (Swedish Government). Read more »
Towards a new retraction record?
The blog Retraction Watch has learned that a widely published Japanese anesthesiologist is under investigation by his university over concerns that he engaged in repeated fraud for decades that has tainted roughly 180 articles — many of which may be retracted as a result. Read more »
AJOB:s former editor leaves company
A controversial bioethicist who has been criticized over conflicts-of-interests issues, yesterday resigned from a Texas company that use stem cells in medical treatments. (ScienceInsider).
Read more »
Should we pay research volunteers?
Researchers almost always offer money as an incentive for healthy volunteers to enroll in research studies, but does payment amount to coercion or undue inducement to participate in research? (EurekAlert! & The Hastings Center). Read more »
New decisions on medical research
The Swedish government present new regulations aimed at fascilitating projects such as LifeGene, the biggest research project ever in Sweden (The Government).
Read more (incl. web presentation) »
WHO wants to publish both avain flu papers
The two very much discussed studies - because of the risk for biological terrorism - should be published in their entirety, WHO now states (ScienceInsider). Read more »
Consensus statement on misconduct
BMJ and COPE have issued a statement on research misconduct in the UK, that defines misconduct broadly and irrespectively of intent. Read the statement.
AJOB editor's departure raises questions
The most successful journal in the bioethics field, American Journal of Bioethics, is suddenly facing trouble as its editor resigns over conflict-of-interest issues (Bioedge). Read more »
On trial for chemical & biological warfare development
There is an inquiry into alleged unethical conduct by a cardiologist - who headed South Africa's chemical and biological warfare programme in the 1980s - by the Health Professions Council of South Africa (Mail & Guardian online). Read more »
New data protection legislation and authority proposed
The EU Commission proposes a comprehensive reform of data protection rules to increase users' control of their data.
Read more »
Protest against stop of infuenza research
Now one of the leading scientists involved in the controversial virus research protests against the decision not to publish results openly. (Vetenskapsradion). Read more »
A stop to open access in the US and UK?
Will the NIH policy on free PubMed access be stopped, and will a similar initiative to end free access by the publishing industry in the UK be successful? (BMJ) Read more »
BMJ Survey of research misconduct
Today BMJ released data on misconduct, saying that 13% reported they had witnessed or had firsthand knowledge of misconduct. Read more »
Influenza research impeded?
The U.S. National Science Advisory Board for Biosecurity, which has asked scientists and journals to redact key details in two explosive influenza papers, is also considering a call for a voluntary broader moratorium on the publication of similar studies while an international debate is held to discuss how the field should proceed (Science). Read more »
Commentary: Don't censor life-saving science (Nature)
Many clinical trials buried
Researchers have found that fewer than half of a sample of trials funded by NIH, had not been published within 30 months of completing the clinical trial. (EurekAlert!). Read more »
Nanosensors = fewer animal experiments?
Researchers hope to have found an alternative approach to animal testing: they hope sensor nanoparticles will reduce the need for it (Fraunhofer). Read more »
Lifegene stopped by Data Inspection Board
Because consent is given to non-specific purposes, the Data Inspection Board ban all handling of personal information in the Lifegene project. (Swedish Data Inspection Board). Read more »
Update: Reaction from scientists (Svenska Dagbladet)
Chimpanzees only for severe conditions
As chimpanzees are so close to humans, NIH should only allow them as subjects in biomedical research under stringent conditions, says a new report (National Research Council). Read more »
More: NIH to follow report recommendations (ScienceInsider).
Alliance slams European Court
The Alliance of German Scientific Organizations has now publicly criticized an ruling from the European Court of Justice that bans patenting of inventions involving human embryonic stem cells as that is immoral (Nature News). Read more »
Animal research can be humane and ethical
Medical researchers who use animals in their work need to do more “to show the public what research labs do”, said noted animal psychologist Temple Grandin (Seattle/LocalHealthGuide).
Read more »
Can solidarity inform bioethics?
Barbara Prainsack and Alena Buyx reflect on this concept and the implications for biobanks (BioNews). Read more »
Trolley dilemma empirically studied
Out of the total number of research participants in a three dimensional setting, given the power to kill one person to save five, about 90 percent are willing to violate a moral rule if it means minimizing harm (Science Daily). Read more »
Prison for illegal & lethal experiments
Four former executives of Synthes Inc. have been sentenced to prison for carrying out human medical trials illegally in which three participants lost their lives (Medical News Today). Read more »
Taiwan to destroy research possibilities
Millions of biomedical samples are set to be destroyed next February due to lack of official participant consent (The China Post). Read more »
More contagious bird flu virus provoke questions
Should you turn a lethal virus into a lethal and highly contagious virus? And then publish how you did it? (NPR) Read more »
Stem cell ruling misleading?
Last month's ruling that inventions derived from human embryonic stem cells are largely unpatentable will shape research. Now, it is claimed that the ruling contains crucial errors with respect to the underlying science (Nature). Read more »
Stem cell patents banned in Europe
The European Court of Justice has ruled that all patents that would require the process of destroying a human embryo at and after the blastocyst stage for stem cell research are banned in Europe (News.com). Read more »
Finally EU patent??
The head of the European Patent Office (EPO) and the European Commissioner for Internal Market and Services today renewed their commitment to introduce a unitary EU patent, which they say would significantly ease workloads and reduce costs for patent applicants (Intellectual Property Watch). Read more »
EU must reform clinical trial regulation
Medical research organisations are urging the European Union to review the regulation of clinical trials because they say that excessive bureaucracy is hampering research into new treatments without enhancing the safety of patients (BMJ). Read more »
Link to statement
'Patent trolls' target biotechnology firms
A US court case in which a firm specializing in patent litigation won, might set a troubling precedent in allowing very broad patents (Nature News). Read more »
On-line informed consent tool
A new multimedia informed consent tool accessed via the Internet may make it easier for cancer patients to understand and feel comfortable enrolling in clinical trials, according a study conducted by researchers in the Perelman School of Medicine at the University of Pennsylvania (EurekAlert!). Read more »
French law make conflict of interest disclosure mandatory
France is contemplating a revamp of its drug approval system and are due to discuss updates to the rules governing disclosures of conflict of interests by experts involved in the country's drug approval process. Read more »
US Patent Reform Signed Into Law
New patent reform legislation aims at helping American entrepreneurs and businesses bring their inventions to market sooner, and convert the ideas from America’s universities and research labs into new products. Read more »
Swedish research council retracts misconduct inquiry
The report on research performed by professor Suchitra Holgersson has been retracted. There are unacceptable question marks surrounding the inquiry. Read more (in Swedish) »
Researchers in Guatemala knew study was unethical
U.S. researchers knowingly breached medical ethics by infecting Guatemalans with venereal diseases in the 1940s without informing them of the risks, a presidential commission has found (Shots Blog)Read more »
EU prepares to re-open REACH 'can of worms''
Only a small number of chemicals get tested properly, so now EU prepares a review of the REACH regulation (EurActiv).
Read more »
New website collecting misconduct cases
A new website, Scientific red cards, is dedicated to taking inventory of scientific publications for which research misconduct has been assessed, and to be a platform for discussing the issue of research integrity.
Authorship rules misleading?
In a recent article, Alastair Matheson claims that rules set up by leading medical journals to define and credit authorship of published articles make it possible to conceal and misrepresent industry contributions to the literature (Science Daily). Read more »
Gene patents decision in the US
While manipulated pieces of DNA might get patented, analyzing gene sequences for alterations is not patentable, ruled a US appeals court recently (Science Insider). Read more »
News in patent law
July 1, 2011 a change was made in the patent law that makes it clear how a demand for inovation doesn't stop patents on new medical uses for old substances (Source: Swedish Government).
Glowing dog might be key to cures
South Korean scientists have created a glowing dog using a cloning technique that could help find cures for human diseases such as Alzheimer's and Parkinson's, Yonhap news agency and Reuters report. Read more »
Consent documents too complex
A review of 124 informed-consent documents used in 21 HIV clinical trials found that the forms were typically too long and use language that is too complex (American Medical News).
Read more »
APS condemns extremism and harassment
In a recent statement, the American Physiological Society condemns the extremist targeting of researchers engaged in legitimate scientific inquiry. Link to statement
Animals containing human material
That is the subject of a recently released report by UK's Academy of Medical Sciences. They believe that the mixing of human and animal material should be approached with great caution. But some highly controversial experiments should be allowed to proceed. Link to report
Rule Changes Proposed for Research on Humans
The US government is now proposing changes to the rules for human subjects research, in order to both strengthen protections and fascilitating important research (New York Times).
Read more »
The great ape debate on its way
In the US, a debate has started on whether it is moral to use primates in research aiming at benefit for man (Nature). Read more »
Blew the whistle - lost the job
An american university denies it retaliated against a researcher who questioned supervisor's data, reports Nature in a thought-provoking news story. Read more »
Shockingly unethical trial
A report on the alleged irregularities in the conduct of an Indian human papilloma virus (HPV) vaccine trial, reveals gross and shocking ethical violations. (The Hindu). Read more »
Drawback for reprogrammed cells
Medical applications of induced pluripotent stem cells are called into question, after cells having trigged immune reactions in mice (Nature). Read more »
Researchers are increasingly resourceful in boosting their online presence and reputation. But getting the right facts out there, and citing and linking to the best, most trustworthy sources of information, are key, writes Nature in an editorial. Läs mer »
Canada needs to investigate research misconduct
Canada needs an independent agency to investigate research misconduct, states an editorial in CMAJ (EurekAlert!). Read more »
US court approve embryonic stem cell research
On 29 April the US Court of Appeals for the District of Columbia Circuit ended the injunction prohibiting government funding of research using human embryonic stem cells, saying that the NIH can use federal money to support research using these cells (BMJ). Read more »
Evidence to medical staff being complicit in torture
In a PLoS Medicine article, Neglect of Medical Evidence of Torture in Guantánamo Bay: A Case Series, the authors relate nine case records of individuals imprisoned at Guantánamo Bay which indicate that medical personnel neglected medical evidence of torture. Read more »
Stop for stem-cell research in Europe?
Ruling on stem-cell patents may spell end of research in Europe, writes The Independent. Read more »
Positive reactions despite increase of administration
The new EU directive on the testing of animals will increase administrative burdens for researchers. Nevertheless, many are positive to the new regulation, Djurförsök.info reports.
Read more »
Easier to do emergency and biobank research
In Denmark a new bill suggests that it be made easier to do research on anonymous biological samples without ethical review and on acutely ill patients without consent. (Forskningsetiske Komiteer). Read more »
Launch of EU trial register
Today the new EU clinical trial register is published on the web. Read more »
Article identifies early phases research problems
A well-noted article in PLoS Medicine argues that early trials do not build on sufficient animal studies and knowledge of earlier studies; deficits that need to be corrected by authorities asking for better basic data in order to approve studies. Read more »
European Court rejects stem-cell patents
The European Court of Justice has issued a preliminary opinion that procedures involving established human embryonic stem (hES) cell lines are not patentable, Nature reports. Read more »
EU patent moves (somewhat) closer
Last week there has been both good and bad news for proponents of a common patent and litigation system in Europe (IP Watch). Read more »
Now 90 articles by the German researcher working in anesthesiology has been retracted (Retraction Watch).
Read more »
First 70, now 11 more retractions
About a year ago, Acta Crystallographica announced it was pulling 70 papers from researchers at a Chinese university after discovering fake reported structures. Now, after an extensive investigation into other papers, 11 more articles are retracted (Retraction Watch). Read more »
Difficult to investigate high-rank administrators
Faculty member allegations over research results at a Japanese university highlight the difficulties of investigating high-ranking administrators, the university president in this case (Nature).
Read more »
Climate change scientists cleared again
In the latest report, from the Commerce Department, UK, leaked e-mails are again said to offer no evidence of misconduct (Daily Mail). Read more »
New article retraction record
A South Corean research group from Suwon now has the dubious modern record in retracted articles: 17! (Retraction Watch)
Read more »
One scandal after another
This harsch judgement comes from Carl Elliott. writer of a new book on how drug companies buy loyalty (Star Tribune).
Read more »
Dangerous medical devices often not tested
American researchers have found that medical devices recalled by the FDA often haven't been subject to clinical trials (EurekAlert!). Read more »
Parliament keeps supporting EU patent
The EU Parliament today is expected to give a green light to the launch of a common patent system without Spain and Italy on board (EurActiv). Read more »
Over 90 articles risk being retracted
After an article penned by a German anesthesiologist was withdrawn in 2009, the inquiry that followed has indicated far more serious concerns. Now over 90 articles documenting clinical trials might be retracted because of a lack of ethical vetting. (Retraction Watch). Read more »
Foreign clinical trials without oversight
A new report reveals that very few trials in developing countries by Western sponsors are ethically approved or monitored by developed country oversight agencies such as the Food and Drug Administration agency (FDA). Read more »
ASM issues ten year ban on publishing
The American Society for Microbiology (ASM), publisher of Infection and Immunity, has now retracted five papers by a Japanese scientist who allegedly mapipulated images. They also banned him from publishing in any of its journals for 10 years. Read more »
Trial registration info included in consent
The FDA has issued a that requires informed consent documents for “applicable” clinical trials to include a statement that information about the trial will be or has been submitted for inclusion in ClinicalTrials.gov’s trial registry, writes Thomson. Read more »
Editorial criticizes over-regulation
In an editorial for Clinical Trials, the existing regulative framework for clinical trials is said to creating "a byzantine maze of bureaucratic steps that emphasize relatively unimportant issues, leading to waste, obstructing the conduct of well-designed important trials, and impeding scientific progress". Read more »
Synthetic biology report under fire
The Presidential Commission today came under fire for not being sufficiently wary of synthetic biology (see below 2010-11-29).
Read more »
Commission opens the way for a unitary patent
The European Commission has presented a proposal opening the way for "enhanced cooperation" to create unitary patent protection in the EU. Such unitary patent protection would allow those Member States that so desired to agree to establish a patent, valid in all participating countries, that could be obtained with a single application. Read more »
German immunologists guilty of misconduct
An investigation committee has found two former postdocs at the Research Center Borstel in Germany guilty of scientific misconduct, Nature writes. Read more »
No strict US rules for synthetic biology
A presidential bioethics commission concluded this week that the U.S. government should not clamp down too hard on research on synthetic biology, a young field that it says doesn't yet pose serious risks (Science). Read more »
EU to revise data directive
Until January 15, the EU Commission has a public consultation over its suggested changes to the EU data protection directive.
Read more »
40's experimentation influence US today
As a response to revelations about unethical research in Guatemala, President Obama has order a review of regulations and protections to ensure that research subjects are properly protected in US research. Read more »
US scientists more likely to fabricate
US scientists are significantly more likely to publish fake research than scientists from elsewhere, finds a trawl of officially retracted studies, and many are repeat offenders (ScienceDaily). Read more »
Mystery fraud accusations
Stem-cell researchers targeted by e-mails from unidentified group (Nature News). Read more »
Update: Nature finds no misconduct
In a recent study, interesting data on how much and where there are plagiarized sections in articles have been found, EurekAlert! informs. Read more »
Commitments in animal ethics committees
In three animal ethics committees, members have been allowed to take part in decisions where there were conflicts-of-interests, something that is now citicised by JO. Read more »
Guidelines for stem cell research postponed
The Swedish Research Council wants to do further work on them in light of recent debate and new legislation, Ny Teknik reports.
Read more »
Updated rules for clinical trials applications
The EU Commission has updated its guidance on how to apply for clinical trials. Therefore LVFS 2003:6 is being revised. One purpose is to make clear the division of labour between the medical products agancies (Läkemedelsverket) and the ethics committees (etikprövningsnämnderna) regarding the vetting and approval of clinical trials. Read more »
PKU biobank not for police
The Swedish Government has decided that the police will not get access to the PKU biobank. Through the bill 3 million blood samples will be kept from all criminal investigations, reports Riksdag & Departement. Read more »
Expert group declines investigation
The expert group concerning research misconduct refuses to investigate an authorship dispute with the justification that authorship is not properly defined in Swedish law. (Läkartidningen).
Read more »
No funding for cheaters
The Swedish Research Council has decided upon new rules concerning funding of people guilty of research misconduct.
Read more »
More: Opinion piece from VR (Svenska Dagbladet)
Plagiarism plagues India's science rep
Transgenic aubergine still banned in India after encouraging report been discredited by plagiarism issues (Nature News). Read more »
Research integrity: Sabotage!
A postdoc destroyed the experiments of a colleague in order to get ahead. It took a hidden camera to expose this malicious side of science (Nature News). Read more »
Gene therapy scandal grows
The number of articles being retracted from a research group in New York just grows (BioNews). Read more »
Adult stem cells as ethically problematic
Hailed as a potential alternative to embryonic stem cells, induced pluripotent stem cells raise their own ethical dilemmas, reports Scientific American. Read more »
Why are we copyrighting science?
An important question gets asked by Varuni de Silva in an opinion piece (BMJ). Read more »
STAN-study cleared of misconduct
Lund University after three years clears the researchers accused of research misconduct in a STAN study (Läkartidningen).
Read more »
Research misconduct worries listed company
The case with a cheating professor in Gothenburg also affects a minor listed company that now ponders whether to give her the boot, writes Affärsvärlden. Read more »
Professor charged with grave misconduct
Seldom has the misconduct group at VR spoken out with such fervor, as in the very last case brought to them (Läkartidningen). Read more »
Ties to industry not disclosed
A new study have found that often even major industry funding is not disclosed to readers of medical journals (EurekAlert!).
Read more »
Misconduct investigation gone astray
Anonymity and the possibility of web publishing means research misconduct investigations could take a turn for the worse (Nature). Read more »
Big apes banned from use in EU research
Great apes such as chimpanzees, gorillas and orangutans are to be banned in research while strict restrictions are set on the use of primates in general. Read more »
Appendix: Questions and answers on the new directive for the protection of animals used for scientific purposes (European Union)
Vaccine's adverse effect kept secret?
At least one Finnish researcher is facing massive critique after it has been revealed that suspicions were kept secret that the vaccine against swine flu might cause narcolepsy, writes Dagens Medicin. Read more »
Confidentiality threatened by subpoenas
When doing research on the health effects of the 1989 Exxon Valdez oil spill, the researcher had to face subpoenas from Exxon lawyers looking for personal information of study subjects. Can litigation risk become an extreme burden on certain types of research? (Nature) Read more »
Ban reintroduced for schimpanzee research
Another bill to ban invasive research on schimpanzees was recently introduced in the US senate, much to the dismay of some researchers (Science). Read more »
Pricey to investigate misconduct
To investigate research misconduct might be very costly, but how should the impact of research misconduct really be measured (Nature). Read more »
Ruling against american stem cell research
A federal court has ruled against President Obama's executive order allowing for more stem cell research (New York Times).
Read more »
Fight over authorship at Karolinska
An infected dispute about proper criteria for authorship will now be handled by the expert group on misconduct. (Läkartidningen). Read more »
Ethics expert from Harvard found cheating
A well known expert on morality and cognition has been found guilty of eight instances of research misconduct (New York Times). Read more »
Plagiarizing professor says he will quit
This summer, we again could read about a case of plagiarizm in media (Dagens Medicin). Read more »
Could publishing a paper make you a spy?
This is fiercly discussed in the states where a chinese scientist is prosecuted after an article on pesticides. (Nature News).
Read more »
Climate researchers cleared of misconduct
Now the last report from The Independent Climate Change Email Review be read on the net.
Stem cell society confuses patients
In a highly critical blog entry, Summer Johnson of Bioethics.net accuses the website of the International Society for Stem Cell Research of bringing on the therapeutic misconception.
Read more »
Journals to use plagiarism software
Publishers including Elsevier and Springer are set to scan submitted papers for identical or paraphrased chunks of text that appear in previously published articles (Nature News).
Read more »
Potential ES cells replacement falls short
A new EU study has found that iPS cells, believed to eliminate the concerns that surround the use of embryonic stem cells, do not have the same scope for use in some applications. Read more »
Gender must be put on the agenda
Still male subjects dominate biomedical research studies. This short-changes women's health, writes Nature in a comment on new studies. Read more »
Prisoners subject to interrogation research
An american group relying on previously classified federal documents, is claiming that torture experimentation and research have been performed on detainees after the US terror attacks of 9/11. (Nature News). Read more »
Embryos not human, rules Korean high court
Embryos that are less than 14 days from insemination have the potential to become a human being but have no independent humanity, the South Korean court ruled last week, BioEdge reports. Read more »
Ignored warnings of scientific misconduct
A controversial scientist who is under misconduct investigation for making false claims in a paper ignored an earlier warning that he could face misconduct charges if the paper was published, Nature News reports. Read more »
Regulations increase cost for research
Ethical reviews criticised
In a press release and a debate article, a group of surgeons criticise a decision in CEPN to not allow a study on patients with ruptured aortic aneurysm without consent. In a similar vein, the ethicist Mats G Hansson has criticised how ethical vetting sometimes hinder important research. Read more »
Study reports often spin results
See further: The JAMA article
JO critical of National Defence College
Researchers at the Swedish college destroyed basic data for the "Malmö report" to protect subjects' anonymity. JO is "very critical" and says that the handling was not in accord with basic guiding principles. Read more »
Dean resigns after misconduct case
The story about a Professor at The Swedish National Defence College who was caught out plagiarizing continues, now the dean resigns because of the turbulence.
Dagens Nyheter comments on the story
WMA President arrested
EU to revise clinical trials directive
After abunding critique the EU now admits that the directive on clinical trials has been deeply flawed. Now a revision is planned. Read more »
Rules & regulations threatens research
In an editorial in CMAJ, the editors present their view that the number of rules and the bureaucracy that comes with them are threatening academic clinical trials which contribute to the public good. Read more »
Indian tribe questions gene research
The researchers collected DNA for the study of diabetes, but also collected wider consent. But when the Havasupai realized that research are being performed that associates tribal genes with schizophrenia (a condition considered stigmatizing), and also research that contradicts traditional stories of origin, they felt betrayed, New York Times reports. Read more »
Would supressed study have altered reach?
Researcher Thomas Hartung (from ECVAM), clearly thinks so. His research, unless supressed by the EU, would have changed the course of the chemical legislation, REACH, in Europe. Read more »
Protests against ape experimentation
Members of Djurrättsalliansen caged themselves, dressed up as monkeys, on the Gustav Adolf square. This is one of several actions in protest against scientific experimentation performed by Smittskyddsinstitutet, Sydsvenskan writes.
Read more »
Closer to animal experimentation directive
EU legislation to regulate the use of animals for scientific experiments has moved a step closer after Parliament and Council representatives reached an agreement on the final details of draft legislation in the pipeline. Read more »
Obama appoints new Bioethics Commission
Now President Obama has appointed new members of his "Commission for the Study of Bioethical Issues". Read more »
Opinion piece on ghostwriting
Gene patent dismissed
It might get harder for companies to take patents on genes, after Myriad Genetics' two patents on breast cancer genes have been dismissed by a federal court in the US, Sveriges Radio reports. Read more »
Implementing EMF directive devastating
The Directive on dangerous Electro-Magnetic Fields (EMF) threatens MRI research, the European Medical Research Councils warn in a fortcoming report.
Read more »
German scientist risks prison after fraud
Dagens Eko warps climate research interview
In an opinion piece at the Newsmill, the radio news program Dagens Eko is accused of misstating what has been said about climate research by one of the leading members of the UN climate panel. Read more »
Swedish research funds more independent
Now many research funds will become more independent of the Swedish state, when board members are to be appointed by others. Read more »
Fat rats skew research results
Failure to recognize that many laboratory animals live unhealthy lives may be leading researchers to misinterpret their findings, potentially misdirecting efforts to develop theraputic drugs, writes Nature News. Read more »
KI head of research suspended
Pain expert faces prison after research fraud
BMJ News relates how a U.S. pain expert falsified medical studies over a period of 15 years. He has pleaded guilty and faces 10 years in prison, as well as having to pay large sums to cheated drug companies and being banned for life from being funded by the FDA. Read more »
Ombudsman probe EU work on animal research
Following allegations of 'maladministration' by a lobby group opposed to all animal testing, the European Ombudsman has opened an investigation of the work by the European Commission. Read more »
Worst ever cheater?
After having been (rightly) accused of fabricating data, the researcher hired actors to testify for him, posing as research subjects. When he won the case, he sued the state and university fo 4 million dollars, reports Ethics Newsline. Read more »
Update: The researcher has now been found dead (from Science Insider).
NIH support requires research ethics
From January 25, the U.S. National Institutes of Health (NIH) in certain cases requires that those receiving financial support for research also participate in research ethics education. This also applies to Swedish researchers doing human subjects research. An application must then include a plan for instruction in responsible conduct of research. Read more »
Embryonic stem cells still vital
New world congress on research integrity
In July, the first world congress, in Lissabon 2007, is followed by a second conference, this time in Singapore, where policy makers from all over the world will gather to discuss better standars for science. Read more »
Are perfectly good articles blocked?
Are citations & impact good meausures?
Common with disregard for author rules
Almost one in two of new doctorates in medicine claim that their articles include scholars as authors that according to the Vancouver rules should not be listed, Läkartidningen writes. Read more »
Fraud big problem in China
No more affirmative action at universities
Now the Government stops the possibility of using affirmative action at Swedish universities, as it has proved to be unfair, argues Tobias Krantz. Read more »
A step closer to new animal testing directive
New legislation regarding the use of animals for scientific experiments is nearer after Parliament and Council representatives reached an agreement of principle on the main issues., eGov Monitor reports. Read more »
Researcher quits because of interference
Study halted because of fear of reprisals
EU-patent is closer
The EU Competitiveness Council has agreed on a general approach to the draft Regulation on the EU patent. Read more »
Too many promises?
Senator investigates ghostwriting practices
U.S. Senator Grassley has written to 10 top medical schools asking what they are doing about professors who put their names on ghostwritten articles in medical journals — and why that practice is any different from plagiarism by students, New York Times reports. Read more »
11 years to debar misconducting doctors
In some instances, it has taken The US Food and Drug Administration up to 11 years to debar doctors who has been fund out engaging in misconduct or even crimes when doing research, a report from the US Government Accountability Office shows.
Read more »
Dishonest statement leads to accusations
A UK researcher didn't get access to all data in a study funded by Procter & Gamble, but the published article stated that "all authors had full access to the data and analyses", BMJ informs.
Read more »
IBC will meet in Mexico
At its 16th meeting, the International Bioethics Committee will discuss cloning and human vunerability. Working documents (reports) are to be found under IBC in the section 'rules and guidelines'. Read more »
Whistleblower got fired
Hwang got a suspended sentence
After a three-year trial, Hwang Woo-Suk, the South Korean stem cell researcher accused of criminal fraud and embezzlement was convicted of embezzling 830 million won ($705,000) in research funds and of illegally buying human eggs for his research. He will not, however, serve any time behind bars, writes The Scientist. Read more »
New conflict rules
Editors of some of the world's top medical journals will soon begin to demand more stringent, uniform reporting of conflicts of interest by researchers, says Wall Street Journal. Read more »
ISSCR to regulate stem cell therapeutics
Image manipulation on the rise
More than meets the RMI
Commission supports nano-regulation
Public Access to Genome-Wide Data
Can individuals be identified through GWD? Should the publication of such data therefore be shut down? Since NIH and the Wellcome Trust recently draw those conclusions, the debate has raged on, here in an article from PLoS Genetics. Read more »
Retracts article by Iran's science minister
Iranian researchers say to Nature, they are dismayed and angered that a 2009 paper coauthored by Kamran Daneshjou, Iran's science minister, appears to have plagiarized a 2002 paper published by South Korean researchers. Read more »
Did HIV-vaccine dump risk on to Thailand?
Cysts halt Geron stem cell trial
Disclosure not sufficient
Disclosure of financial conflicts of interests to potential participants in research is important, but may have a limited role in managing these conflicts, according to a new study by Johns Hopkins, Duke and Wake Forest. Read more »
Greater animal use after REACH?
Implementation of REACH legislation may require 54 million research animals and €9.5 billion over the next 10 years, which represents 20 times the number of animals and six times the cost anticipated in previous estimates, writes EurekAlert. Read more »
EU law 'putting brakes on science'
EurActiv.com reports that, according to a leading academic, european rules on medical research have decimated academic studies due to spiralling insurance costs and bureaucracy.
Read more »
Should child donors have their say?
REACH misses nano!
Ghostwriters pushed therapy
Wyeth, a pharmaceutical company, paid a medical communications firm to draft scientific papers, apparantley to promote the sales of its hormone drugs, writes The New York Times. Read more
New GCP inspections initiative
The European Medicines Agency and the US Food and Drug Administration have agreed to launch a joint initiative to collaborate on international Good Clinical Practice (GCP) inspection activities. Read more »
Journal retracts artificial sperm paper
The journal which published a startling paper claiming to have derived sperm cells from human embryonic stem cells has taken the radical step of retracting it because of plagiarism, BioEdge reports. Read more »
NIH human stem cell research guidelines
National Institutes of Health finally issues research guidelines, taking President Obama's executive order into account.
Read more »
EU legislation increases workloads
The Past, Present, and Future of Bioethics
In this commentary, Susan Gilbert relates the 40-year history of the Hastings Center and asks what the future might bring.
Read more »
Hoax paper challenges Open Access
Women underrepresented in cancer research
'Outsourcing' clinical trials devastating?
Canadian researchers studying the effects of a heart drug tried to expedite the experiment by farming out much of their clinical-trial work to developing countries, but the study results there turned out to be largely fraudulent, writes National Post. Read more »
How Many Fabricate and Falsify Research?
In PLoS, Daniele Fanelli reports the first meta-analysis of surveys about misbehaviour. The results suggest that making up data is more frequent than previously thought. Read more »
Fight over biobank material continues
When material is to be moved at the Umeå biobank, questions about confidentiality and rights return. Read more (in Swedish) »
Lawsuit challenges patenting of human genes
Patents have been awarded on human genes for decades, but until last week, no one had directly challenged the underlying idea that genes can be owned in a U.S. court. Now, a challenge has begun, Science tells us. Read more »
Article retracted after 8 years
New research ethics library
A new webpage on research ethics, Forskningsetisk bibliotek (FBIB), has over 60 newly written articles and case studies and movies too. FBIB is created by Norways Forskningsetiske komiteer. Read more »
OECD on research misconduct
In a new report, OECD has included a guide for how to investigate allegations of research misconduct. Read more »
Should we conduct research on torture?
New law on secrecy and public documents
The new law will be in force from June 30 2009. It is a rewrite of the Secrecy Act with the purpose of making the regulation easier to understand and use in practice. Read more »
One's ethics varies with time
When a moral judgment concerns something near in time, the ethics suffers, according to a Psychology dissertation by Jens Agerström, Lund University. Read more »
Researchers should share failed experiments
In a commentary in the Economist on the proposed European rules governing animal experiments, the commission’s proposal that scientists who use animals should share data (subject to confidentiality) from failed experiments is lauded. Read more »
Public inquiry on clinical research completed
The final report was presented recently. Read more »
Anger after EU vote
Merck behind phony journal
Merck has made up a phony, but real sounding, peer reviewed journal and published favorably looking data for its products in them. Read more »
Stem cell research returns to South Korea
South Korea has conditionally lifted a ban on stem cell research using human eggs, three years after outlawing the practice because a scientist was found to have faked his work, Google/AFP reports. Read more »
VR writes EU concerning animal directive
The Swedish Research Council has, together with a number of other Swedish authorities and organisations, sent a letter to the 19 Swedish parlamentarians, concerning the new EU laboratory animal directive (that has been reported on in earlier news). Read more »
The Wild West of Nanotechnology
In a field growing exponentially with minimal regulation, significant venture capital and government funding, and even more opportunity for professional advancement and financial gain, there is also opportunity for ethical missteps, cutting corners, cheating, and outright criminal activity to take place, writes Summer Johnson in her blog on bioethics.net. Read more »
Research misconduct: Science retracts article
Science is retracting an 2005 article on the MAGIC method without the agreement of all authors. Read more ».
Doctor has cloned human embryos?
'Phase 0' Trials to Speed Drug Development
Studio ett on whistleblowing
The EU seeks a global regulation of science
In a new report to the Commission, it is urged, among other things, that scientists publish in open access journals and that the Commission works towards a global regulation of science. Read more »
Nigeria and Pfizer to settle
Nigeria's Kano state and drugmaker Pfizer Inc have agreed the broad terms of an out-of-court settlement in a multi-billion-dollar lawsuit over a 1996 drug trial, reports Reuters. Read more »
Joy and anger over animal-research vote
Law on medical devices amended
Through a decision in the Swedish Riksdag the law has been amended to incorporate an EC directive among other things. Read more »
Open access stirs US debate
The story of Dr. Leo and the journal
A conflict between a "whistleblower" and the journal JAMA - told in Bioethics Discussion Blog - leads to question about academic freedom and the right way to handle accusations of ethical misconduct. Read more »
European clinical trial rules under fire
Millions wasted by duplicating research
The European Union is wasting billions by investing in new research projects which have already been done by other European scientists, Roland Strauss of Knowledge4Innovation told EurActiv in an interview. Improved communication between research institutes and better use of existing patents could lead to sizeable savings, he said. Read more »
New thesis on ambivalence in academia
Anders Jörnesten, Uppsala University, Department of Sociology: Forskningens nytta: Om ambivalens i forskningspolitik och vardag. Read more »
Bioethics Briefing Book
From Birth to Death and Bench to Clinic: The Hastings Center Bioethics Briefing Book for Journalists, Policymakers, and Campaigns contains 36 overviews of issues in bioethics of high public interest, such as abortion, health care reform, human and sports enhancement, organ transplantation, personalized medicine, medical error, and stem cells. The chapters, written by leading ethicists, are nonpartisan, presenting reasonable considerations from various perspectives that are grounded in good scientific and ethical facts. Read more »
EU says no to stem cell patents
European patent law prohibits the patenting of human stem cell cultures whose preparation necessarily involves the destruction of human embryos. This is the decision reached by the Enlarged Board of Appeal of the European Patent Office (EPO).
Read more »
Link: European Patent Office: No European patent for WARF/Thomson stem cell application
Oxford bioethics centre comes under fire
A UK philosopher has made a stinging attack on Julian Savulescu’s Uehiro Centre for Practical Ethics at Oxford University. In an address to students at Oxford Professor David Oderberg, of the University of Reading, says that it should be radically reformed or closed. Read more »
Helsinki declaration revised
At the WMA General meeting in Seoul a revised version of the wellknown Helsinki declaration was adopted. It includes several minor changes, as well as a demand that all clinical trials be registred in a public database before inclusion of research subjects.
New journal: Bioethica Forum
Bioethica Forum, the Swiss Journal of Biomedical Ethics, was launched in June 2008. The first issue is freely available online at: http://www.bioethica-forum.ch. Bioethica Forum is a trilingual interdisciplinary, peer-reviewed journal focussing on issues in biomedical ethics, published by the Swiss Society for Biomedical Ethics.
Globethics - new portal for etics resources
Globethics.net is a global network of persons and institutions interested in different fields of applied ethics. It offers access to resources on ethics, especially through its leading global digital library on ethics. In addition, it facilitates collaborative web-based research, conferences, online publishing and active sharing of information.
Globethics.net aims especially at increasing the visibility of, and access to ethics perspectives from Africa, Latin America and Asia. It strengthens global common values and respect of ethical contextual diversity, including the richness of languages, religions and world views.
The latest news are published on the start page of CODEX!
Last update: 2014-10-23